Type 1 versus type 3 neovascularization in pigment epithelial detachments associated with age-related macular degeneration after anti-vascular endothelial growth factor therapy: a prospective study

X Chen, M Al-Sheikh, CK Chan, AH Hariri, P Abraham… – RETINA, 2016

Purpose: To evaluate the response to aflibercept therapy for Type 1 and Type 3 neovascularization in pigment epithelial detachments associated with treatment-naive, neovascular age-related macular degeneration. Methods: In this multicentered, …

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Integration of Growth Factor Gene Delivery with Collagen‐Triggered Wound Repair Cascades using Collagen‐Mimetic Peptides

MA Urello, KL Kiick, MO Sullivan – Bioengineering & Translational Medicine, 2016

ABSTRACT Growth factors (GFs) play vital roles in wound repair. Many GF therapies have reached clinical trials, but success has been hindered by safety concerns and a lack of efficacy. Previously, we presented an approach to produce protein factors in wound beds …

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Transforming growth factor beta 1 increases collagen content, and stimulates procollagen I and tissue inhibitor of metalloproteinase-1 production of dental pulp cells

PS Lin, HH Chang, CY Yeh, MC Chang, CP Chan… – Journal of the Formosan …, 2016

Methods Pulp cells were exposed to TGF-β1 with/without pretreatment and coincubation by 1, 4-diamino-2, 3-dicyano-1, 4-bis (o-aminophenyl mercapto) butadiene (U0126; a mitogen-activated protein kinase kinase [MEK]/extracellular signal-regulated kinase [ERK] inhibitor …

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Evaluation of Epidermal Growth Factor-Incorporating Skin Care Product in Culture Experiment Using Human Fibroblasts

A Yamamoto, H Ohno, Y Kuroyanagi – Open Journal of Regenerative Medicine, 2016

This study aimed to investigate the potential of a skin care product composed of hyaluronic acid (HA) and collagen (Col) sponge containing epidermal growth factor (EGF), vitamin C derivative (VC), glucosylceramide (GC), poly (γ-glutamic acid)(PGA), and argentine (Arg). ...

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